Treatment for liver cancer

Main treatments for liver cancer

Liver cancer is often treatable, but it can be difficult to treat.

The treatment you have will depend on:

It may include surgery, chemotherapy, using heat to destroy the cancer (thermal ablation), targeted medicines, and radiotherapy.

The specialist care team looking after you will:

You'll have regular check-ups during and after any treatments. You may also have tests and scans.

If you have any symptoms or side effects that you are worried about, talk to your specialists. You do not need to wait for your next check-up.


If liver cancer is found early, is small and it has not spread, you may be able to have surgery to remove it.

Surgery will remove part or all of your liver. If it's all removed you will need a liver transplant to replace your liver with a donated one.

Recovery from surgery to treat liver cancer can take a long time. The specialist team looking after you will discuss all the benefits and side effects.


Chemotherapy uses medicines to kill cancer cells.

For liver cancer, the chemotherapy medicine is usually given into the blood vessels of the cancer. It aims to stop the cancer growing. This is called chemoembolisation.

You'll usually have chemoembolisation to help make the cancer smaller, or to control and improve the symptoms.

This is done if you are not able to have surgery because you are very unwell, or the cancer cannot be removed by surgery.

Using heat to destroy the cancer (thermal ablation)

Thermal ablation uses an electric current or microwaves to destroy the cancer.

You may have thermal ablation to treat liver cancer if you're not able to have surgery because you are very unwell, or the cancer cannot be removed by surgery.

Targeted medicines

Targeted cancer medicines aim to stop the cancer from growing.

You may have treatment with targeted medicines for liver cancer if:


Radiotherapy is where radiation is used to kill cancer cells.

A type of radiotherapy called selective internal radiation therapy (SIRT) is sometimes used to treat liver cancer. This is where radioactive beads are injected into your liver's blood supply to stop the cancer growing.

You may have SIRT for liver cancer if you're an adult and:

What happens if you’ve been told your cancer cannot be cured

If you have advanced liver cancer it might be very hard to treat. It may not be possible to cure the cancer.

If this is the case, the aim of your treatment will be to limit the cancer and its symptoms, and help you live longer.

Finding out the cancer cannot be cured can be very hard news to take in.

You will be referred to a special team of doctors and nurses called the palliative care team or symptom control team.

They will work with you to help manage your symptoms and make you feel more comfortable.

The clinical nurse specialist or palliative care team can also help you and your loved ones get any support you need.

Page last reviewed: 13 June 2023
Next review due: 13 June 2026