Sjögren's syndrome

Sjögren's (pronounced show-grins) syndrome is a condition that affects parts of the body that produce fluids, like tears and spit (saliva).

It usually starts in people aged 40 to 60 and is much more common in women than men.

It's a long-term condition that can affect your daily life, but there are treatments to help relieve the symptoms.

Symptoms of Sjögren's syndrome

The symptoms of Sjögren's syndrome include:

When to see a GP

See a GP if you have symptoms of Sjögren's syndrome that do not go away or are bothering you.

There are many things that can cause similar symptoms. The GP can check for some of the more common causes, such as swelling of the eyelids (blepharitis)diabetes or side effects from medicine.

If needed, they can refer you to a specialist for further tests, such as:

Find out more about the tests for Sjögren's syndrome.

Things you can do if you have Sjögren's syndrome

To help relieve the symptoms of Sjögren's syndrome:

Treatments for Sjögren's syndrome

There's currently no cure for Sjögren's syndrome, but there are several treatments that can help, such as:

Causes of Sjögren's syndrome

Sjögren's syndrome is caused by the immune system (the body's defence against infection), damaging healthy parts of the body. This is known as an autoimmune condition.

The condition usually affects areas of the body that produce fluids, such as tears and saliva. But other parts of the body, such as nerves and joints, can also be affected.

It's not clear why the immune system stops working properly.

It may be linked to:

Sometimes, people with Sjögren's syndrome also have other autoimmune conditions, such as rheumatoid arthritis or lupus. This is known as secondary Sjögren's syndrome.

Primary Sjögren's syndrome is where you do not have any other related conditions.

Living with Sjögren's syndrome

Sjögren's syndrome is a long-term condition that does not usually get better on its own, although the symptoms can often be treated.

For some people it may just be a bit of a nuisance, while for others it can have a big impact on their daily life.

Some people may develop complications of Sjögren's syndrome, such as problems with their vision or lungs.

There's also a slightly increased risk of a type of cancer called non-Hodgkin lymphoma.

If you're diagnosed with Sjögren's syndrome, ask your doctor about what you can expect.

You may also find it useful to contact organisations such as the British Sjögren's Syndrome Association (BSSA) for advice and support.

Page last reviewed: 21 April 2020
Next review due: 21 April 2023